R2101053 |
ML298 |
ML298 (CID53393915) is a potent, specific inhibitor of Phospholipase D2 (PLD2) w
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R2101054 |
SW155246 |
SW155246 is a potent and selective DNMT1 (DNA methyltransferase 1) inhibitor wit
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R2101055 |
ML-299 |
ML299 (VU0463568) is a dual inhibitor of PLD1 and PLD2 with IC50 of 6 nM and 20
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R2101056 |
VUF11418 |
VUF11418 is a nonpeptidomimetic agonist of the G protein-coupled chemokine recep
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R2101057 |
CGS-15943 |
CGS15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor
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R2101058 |
NSC177223 |
API-1 (NSC 177223) is a potent inhibitor of Akt that induces GSK3-dependent, β-T
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R2101059 |
ML162 |
一种小分子探针,选择性杀死诱导表达突变RAS的细胞;抑制BJeLR(表达HRAS G12V)细胞系,IC50为25 nM,显示出比BJeH LT(不含HRAS
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R2101060 |
GSK-843 |
GSK-843 是一种受体相互作用蛋白激酶 3 (RIP3 or RIPK3) 抑制剂,高亲和力结合 RIP3 激酶结构域,IC50 值为 8.6 nM,并抑制
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R2101061 |
Imidazenil |
Imidazenil is a GABA-A modulator that blocks the sedative effects without loweri
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R2101062 |
FIT-039 |
FIT-039 是一种选择性,ATP 竞争性且具有口服活性的 CDK9 抑制剂,对 CKD9/cyclin T1 的 IC50 为 5.8 μM。FIT-039
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R2101063 |
SR8278 |
SR8278 是一种竞争性核血红素受体 REV-ERB 合成拮抗剂。SR8278 抑制 REV-ERBα 转录活性,EC50 为 0.47 μM。SR8278
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R2101064 |
VPC23019 |
VPC23019,一种含芳基酰胺的鞘氨醇 1-磷酸 (S1P) receptor 调节剂,S1P1 和 S1P3 受体的竞争性拮抗剂 (pKis=7.86 和
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R2101065 |
HS-1793 |
HS-1793 is a stable resveratrol analog that protects cardiac against mitochondri
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R2101066 |
Mycro3 |
Mycro 3 是一种有效的选择性 c-Myc 抑制剂。
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R2101067 |
RBC10 |
RBC10 is an inhibitor of Ral binding to RALBP1 (the effector).
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R2101068 |
PD089828 |
PD-089828 是 ATP 竞争性 FGFR-1、PDGFR-β 和 EGFR (IC50 分别为 0.15, 1.76, 5.47 µM) 抑制剂和 c-
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R2101069 |
CRANAD-28 |
CRANAD-28, a blood brain barrier (BBB) penetrable two-photon imaging probe, acts
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R2101070 |
BPU-11 |
BPU-11 is a HCN4 CLP ligand. It acts by modulating channel function and complete
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R2101071 |
CE3F4 |
CE3F4 是一种选择性的 Epac1 拮抗剂,对 Epac1 和 Epac2(B) 的 IC50 值分别为 10.7 μM 和 66 μM。
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R2101072 |
NIBR-0213 |
A potent, selective, orally active S1P1 antagonist with IC50 of 2.5 nM Ca2+ mobi
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R2101073 |
BDP5290 |
BDP5290 是 ROCK 和 MRCK 的有效抑制剂,对于 ROCK1,ROCK2,MRCKα 和 MRCKβ 的 IC50 值分别为 5 nM,50 nM
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R2101074 |
PH-064 |
PH-064 (BIM-46187) 是摘自专利FR 2879460 A1中的钠离子通道抑制剂。
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R2101075 |
ry785;Kv2-IN-A1 |
Kv2-IN-A1 is a Kv2.1 and Kv2.2 inhibitor.
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R2101076 |
DD1 |
DD1 is a proteasome inhibitor that induces human myeloid tumor-selective apoptos
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R2101077 |
AEM1 |
NRF2抑制剂AEM1是癌细胞中NRF2转录活性的特异性小分子抑制剂,对一组>100种激酶(包括PI3K,AKT和PKC的同种型)没有活性;广泛降低NRF
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