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首页 > 产品展示 > Apoptosis
目录号 产品名称 产品描述
R10005 AT-406 (Synonyms: SM-406; Debio-1143) AT-406 是一种有效的,可口服的 Smac 模拟物,为 IAPs 的拮抗剂,能够抑制 XIAP,cIAP1 和 cIAP2 蛋白,Ki 值分别为 66.4,
R10039 Venetoclax; ABT-199; GDC-0199 Venetoclax (ABT-199, GDC-0199) is a Bcl-2-selective inhibitor with Ki of 4800-fo
R10094 NSC 652287 RITA (NSC 652287) induces both DNA-protein and DNA-DNA cross-links with no detec
R10095 Tenovin1 Tenovin-1 protects against MDM2-mediated p53 degradation, which involves ubiquit
R10119 PAC-1 (Synonyms: Procaspase activating compound 1) PAC-1 是一种 procaspase-3 激活剂,诱导癌细胞凋亡,EC50 为 2.08 μM。
R10257 VX765; Belnacasan Belnacasan (VX-765) is a potent and selective inhibitor of caspase-1 with Ki of
R10333 Navitoclax (Synonyms: ABT-263) Navitoclax (ABT-263) 是有效,可口服的 Bcl-2 抑制剂,可与Bcl-xL,Bcl-2, Bcl-w等多种Bcl-2家族蛋白结合,Ki 值
R10350 UMI-77 UMI-77 is a selective Mcl-1 inhibitor with Ki of 490 nM, showing selectivity ove
R10362 GSK2606414 GSK2606414 is an orally available, potent, and selective PERK inhibitor.
R10370 GSK2656157 GSK2656157 is an ATP-competitive inhibitor of PERK enzyme activity with an IC(50
R10425 Spautin1 Spautin-1 is a novel autophagy inhibitor, IM inhibited the growth of K562 cells
R10511 Lenalidomide; CC5013 Lenalidomide (CC-5013) is a TNF-α secretion inhibitor with IC50 of 13 nM in PBMC
R10553 Venetoclax; ABT199 Venetoclax (ABT-199; GDC-0199) 是一种高效,有选择性和口服活性的 Bcl-2 抑制剂,Ki 小于0.01 nM。 
R10603 JNJ26854165 JNJ-26854165 (Serdemetan) acts as a HDM2 ubiquitin ligase antagonist and also in
R10628 Apoptosis Activator2 Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and
R10655 Necrostatin-1 Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosi
R10763 Kevetrin hydrochloride; NSC525990 Kevetrin hydrochloride is a small molecule and activator of the tumor suppressor
R10786 FMK FMK is a RSK2 kinase inhibitor.
R10798 LCL161 LCL161 is an orally bioavailable second mitochondrial-derived activator of caspa
R10799 LCL161 Enantiomer LCL161 is an orally bioavailable second mitochondrial-derived activator of caspa
R10802 Nutlin-3 MDM2 antagonist nutlin-3 is a potent inducer of apoptosis.
R10827 RG7112 (Synonyms: RO5045337) RG7112 是有效的、选择性的、第一个用于临床的、可口服的、可透过血脑屏障的、 MDM2-p53 抑制剂,IC50 值为 18 nM,结合到MDM2 的KD
R11535 NSC59984 NSC59984 is a p53 pathway activator via induction of mutant p53 protein degradat
R11566 Tasisulam Tasisulam is an antitumor agent and an apoptosis inducer via the intrinsic pathw
R11638 Emricasan, (IDN-6556; PF-03491390) Emricasan (PF 03491390)是不可逆的 pan-caspase 抑制剂。 
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