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目录号 | 产品名称 | 产品描述 |
R10004 | Lumacaftor (VX-809; VRT 826809) | Lumacaftor (VX-809; VRT 826809) 是 CFTR 调节剂,可纠正 CFTR 蛋白的折叠和运输。 |
R10109 | VX661 | VX-661 is a second F508del CFTR corrector and is believed to help CFTR protein r |
R10141 | SB705498 | SB705498 is a TRPV1 antagonist for hTRPV1, antagonizes capsaicin, acid, and heat |
R10227 | TAK438; Vonoprazan Fumarate | Vonoprazan Fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid block |
R10266 | GlyH101;GlyH-101 | GlyH-101是可渗透入细胞的CFTR阻断剂,Ki为1.4 uM。 |
R10411 | Ivacaftor;VX770 | 依伐卡托 Ivacaftor是一种有效可口服的 CFTR 增效剂,靶向G551D-CFTR和F508del-CFTR的EC50分别为100 nM 和 25 nM |
R10438 | Dronedarone Hydrochloride | Dronedarone HCl is a therapy for the treatment of patients with paroxysmal and p |
R10439 | Fasudil; HA-1077 | HA-1077 inhibits vascular smooth muscle contraction by acting as an intracellula |
R10487 | PTC124 | Ataluren (PTC124) selectively induces ribosomal read-through of premature but no |
R10834 | Vinpocetine | Vinpocetine is a selective inhibitor of voltage-sensitive sodium channel for the |
R10973 | CB-5083 | CB-5083是有效,选择性和有口服活性的 p97 抑制剂,IC50 值为 11 nM。 |