R10445 |
Probucol |
Probucol (DH-581) 能抗血脂过多,能通过增加LDL的代谢率降低血液中的胆固醇水平。
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R10447 |
Capecitabine |
Capecitabine is a tumor-selective fluoropyrimidine carbamate, which achieves hig
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R10448 |
Imatinib; STI571 |
Imatinib (STI571) is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC5
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R10449 |
Gefitinib; ZD1839 |
Gefitinib (ZD-1839) is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992
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R10450 |
Erlotinib; NSC718781; OSI744; R1415 |
Erlotinib (CP-358774) 是一种直接作用的 EGFR 酪氨酸激酶抑制剂,对人 EGFR 的 IC50 为 2 nM。Erlotinib 可降低
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R10451 |
Ondansetron; GR38032 |
Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemeti
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R10452 |
Tropisetron; Novaban; SDZ-ICS930 |
Tropisetron HCl is a potent and selective 5-HT3 receptor antagonist and α7-nicot
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R10453 |
ExemestaneF; CE24304 |
Exemestane is an aromatase inhibitor, inhibits human placental and rat ovarian a
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R10454 |
Mesna; Sodium 2-mercaptoethanesulfonate |
Mesna, a sulfhydryl compound that is used to reduce the incidence of hemorrhagic
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R10455 |
Granisetron |
Granisetron is a serotonin 5-HT3 receptor antagonist used as an antiemetic to tr
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R10456 |
Gimeracil |
Gimeracil is an inhibitor of dihydropyrimidine dehydrogenase, which inhibits the
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R10457 |
Irinotecan;; +-Irinotecan; CPT-11 |
rinotecan is a topoisomerase I inhibitor for LoVo cells and HT-29 cells with IC5
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R10458 |
Etoposide; VP16; VP16213 |
Etoposide is a semisynthetic derivative of podophyllotoxin, which inhibits DNA s
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R10459 |
Potassium oxonate |
Oxonic acid potassium salt is an inhibitor of uricase, oxonic inhibits the phosp
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R10461 |
Trelagliptin |
Trelagliptin(SYR-472)是长效的DPP4抑制剂,可作用于2型糖尿病。
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R10466 |
Mianserin hydrochloride |
Mianserin盐酸盐是H1受体反向激动剂,有抗抑郁活性。
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R10478 |
Cefotetan |
Cefotetan 是一种半合成的头霉素抗生素,通过抑制细胞壁合成发挥杀菌作用。
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R10482 |
Tadalafil |
Tadalafil is a PDE-5 inhibitor with IC50 of 1.8 nM in a cell-free assay.
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R10483 |
IDO-IN1 |
IDO-IN-1 是一种有效的吲哚胺-2,3-双加氧酶 (IDO) 抑制剂,IC50 为 59 nM。
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R10484 |
IDO-IN-2;IDO5L |
IDO5L 是一种有效的吲哚胺-2,3-双加氧酶 (IDO) 抑制剂,IC50 为 67 nM
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R10485 |
Epacadostat (Synonyms: INCB 024360) |
Epacadostat (INCB 024360) 是一种有效,选择性的 IDO1 抑制剂, IC50 为 71.8 nM±17.5 nM。
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R10486 |
TEPP46; ML265 |
TEPP-46 是一种有效,选择性的丙酮酸激酶 M2 (pyruvate kinase M2) 激活剂,AC50 值为 92 nM,对 PKM1,PKL 和 P
|
R10487 |
PTC124 |
Ataluren (PTC124) selectively induces ribosomal read-through of premature but no
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R10488 |
Empagliflozin |
Empagliflozin是一种选择性钠葡萄糖协同转运蛋白-2 (SGLT-2) 抑制剂,抑制人SGLT-2的IC50 为3.1 nM。
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R10489 |
Canagliflozin hemihydrate |
Canagliflozin 0.5 H2O(JNJ 28431754; TA 7284) is a highly potent and selective SG
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