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目录号 | 产品名称 | 产品描述 |
R10411 | Ivacaftor;VX770 | 依伐卡托 Ivacaftor是一种有效可口服的 CFTR 增效剂,靶向G551D-CFTR和F508del-CFTR的EC50分别为100 nM 和 25 nM |
R10412 | Vemurafenib (PLX4032, RG7204) | Vemurafenib (PLX4032, RG7204)是一种新型有效的B-RafV600E抑制剂,IC50为31 nM。Vemurafenib对B-RafV |
R10414 | Lomeguatrib | Lomeguatrib is a potent inhibitor of O6-alkylguanine-DNA-alkyltransferase with I |
R10415 | AZD1981 | AZD1981 is a potent, selective CRTh2 (DP2) receptor antagonist with IC50 of 4 nM |
R10417 | EHop016 | EHop-016是Rac GTPase高效选择性抑制剂,在MDA-MB-435细胞中IC50值1.1uM。 |
R10421 | Optovin | Optovin是可逆性光敏TRPA1激活剂,斑马鱼模型中可通过光敏活性观察其运动行为。 |
R10422 | BRD73954 | BRD73954 是一种有效的选择性HDAC抑制剂, 作用于HDAC6和HDAC8, IC50分别为36 nM和120 nM。 |
R10423 | STF118804 | STF-118804 is a highly specific NAMPT inhibitor. |
R10424 | JNJ26481585; Quisinostat | Quisinostat (JNJ-26481585) 是一种有口服活性,高效的 HDAC 抑制剂,对 HDAC1,HDAC2,HDAC4,H |
R10425 | Spautin 1 | Spautin-1 is a specific and potent autophagy inhibitor which inhibits |
R10429 | Doxorubicin hydrochloride | Doxorubicin (Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase |
R10430 | Rapamycin; Sirolimus | Rapamycin (Sirolimus; AY 22989) 是一种有效且特异性的 mTOR 抑制剂,作用于 HEK293 细胞,抑制 mTOR,IC50 为 |
R10431 | Mitomycin C; Ametycine | Mitomycin C is a DNA crosslinking agent that inhibits DNA synthesis and induces |
R10432 | Rivaroxaban; Xarelto; BAY 59-7939 | Rivaroxaban is a direct inhibitor of Factor Xa with Ki and IC50 of 0.4 nM and 0. |
R10433 | Prasugrel | Prasugrel is a thienopyridine ADP receptor (P2Y12) antagonist, used for the redu |
R10434 | PR171; Carfilzomib | Carfilzomib是不可逆的蛋白酶体 (proteasome) 抑制剂,其在ANBL-6和RPMI 8226细胞中的 IC50 为5 nM。 |
R10435 | Linagliptin; BI1356 | Linagliptin 是一种有效,选择性的 DPP-4 抑制剂,IC50 值为 1 nM。 |
R10436 | Ambrisentan; BSF208075; LU208075 | Ambrisentan 是一种选择性的ET A型受体 (ETAR) 拮抗剂。 |
R10437 | Darusentan | Darusentan 是一种选择性内皮素 A (endothelin A; ETA) 受体拮抗剂。Darusentan 在大鼠主动脉血管平滑肌细胞 ( |
R10438 | Dronedarone Hydrochloride | Dronedarone HCl is a therapy for the treatment of patients with paroxysmal and p |
R10439 | Fasudil; HA-1077 | HA-1077 inhibits vascular smooth muscle contraction by acting as an intracellula |
R10440 | Esmolol | Esmolol是心脏选择性β1阻断剂,能迅速发挥作用、持续时间短,在治疗剂量下,对内在拟交感活性或膜稳定性没有显著影响。 |
R10442 | Milrinone | Milrinone 是 PDE3 抑制剂,也是一种强心药、血管舒张药。 |
R10443 | Carvedilol; BM14190 | Carvedilol is a non-selective beta blocker/alpha-1 blocker, used to treat conges |
R10444 | Olprinone | Olprinone(Loprinone) is a selective phosphodiesterase 3 (PDE3) inhibitor. |