R10626 |
xL019; SAR245409 |
Voxtalisib (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ
|
R10627 |
ICILIN |
Icilin is a cooling agent that activates the novel cold receptors TRPM8 (CMR1) a
|
R10628 |
MDK83190 |
MDK83190 是一种有效的细胞凋亡 (apoptosis) 激活剂,诱导 Apaf-1 寡聚化,以 cyto-c 依赖性方式增加 procaspase-9
|
R10629 |
Dapivirine; TMC-120 |
Dapivirine (TMC120) is a non-nucleoside inhibitor for HIV reverse transcriptase
|
R10630 |
Siramesine Hydrochloride |
Siramesine Hydrochloride is a selective sigma-2 receptor agonist, which has been
|
R10631 |
SiramesineLu-28-179 |
Anti-cancer agent siramesine is a lysosomotropic detergent that induces cytoprot
|
R10632 |
AGI-6780 |
AGI-6780 is a potent, selective inhibitor of mutant IDH2 with an IC50 value of 2
|
R10634 |
Betrixaban |
Betrixaban 是一种口服有效的选择性 factor Xa (fXa) 抑制剂,IC50 为 1.5 nM。
|
R10637 |
Methylisoindigotin |
Meisoindigo, a derivative of Indigo naturalis, is a promising agent with in vitr
|
R10642 |
Des(benzylpyridyl) Atazanavir |
Atazanavir is a highly effective HIV-1 protease inhibitor.
|
R10643 |
VGX-1027 |
VGX-1027 is an orally active immunomodulator. Phase 1.
|
R10644 |
Y320 |
Y-320是免疫调节剂,能抑制IL-15刺激CD4 T细胞后的IL-17生成,IC50为20到60 nM。
|
R10645 |
Atglistatin |
Atglistatin 是一种选择性的脂肪甘油三酯脂酶 (ATGL) 抑制剂,体外抑制脂解作用,IC50 为 0.7 μM。
|
R10646 |
Ametantrone ;NSC196473 |
Ametantrone (AM) is a synthetic 9,10-anthracenedione bearing two (hydroxyethylam
|
R10648 |
Dimethyloxaloylglycine;DMOG |
DMOG is an antagonist of α-ketoglutarate cofactor and inhibitor for HIF prolyl h
|
R10649 |
P7C3 |
P7C3 is a potent proneurogenic and neuroprotective chemical that targets NAMPT e
|
R10650 |
(R)-P7C3-Ome |
P7C3 is a drug related to latrepirdine (dimebon), which has neuroprotective and
|
R10656 |
CP-640186;CP640186 |
CP-640186 是一种有效且可透过细胞的 乙酰辅酶A羧化酶 (ACC) 抑制剂,抑制大鼠肝脏 ACC1 和大鼠骨骼肌 ACC2 的 IC50为 53 nM
|
R10657 |
CID797718 |
|
R10658 |
PR-619 |
PR-619 is a non-selective, reversible inhibitor of the deubiquitinylating enzyme
|
R10659 |
Fenretinide; 4-HPR |
Fenretinide is a synthetic retinoid agonist. It is an antiproliferative, antioxi
|
R10661 |
KPT-330 |
KPT-330 is a CRM1-selective inhibitor of nuclear export. It inhibits protein tra
|
R10662 |
TTP22 |
TTP 22 is a high affinity, casein kinase 2 (CK2) inhibitor (IC50= 0.1uM, Ki= 40n
|
R10663 |
5SrRNAmodificator |
|
R10664 |
CM 346; Obenoxazine HCl |
CM 346 is an anxiolytic drug, produces anxiolytic and neuroprotective effects wi
|