R10311 |
E7080; E7080; Lenvatinib Intermediate3 |
Neratinib (HKI-272) is a highly selective HER2 and EGFR inhibitor with IC50 of 5
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R10312 |
E7080; E7080; Lenvatinib Intermediate4 |
Neratinib (HKI-272) is a highly selective HER2 and EGFR inhibitor with IC50 of 5
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R10313 |
KU0059436; AZD2281; OlaparibIntermediate |
Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5
|
R10314 |
PD0332991; PD0332991; Palbociclib |
Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 wi
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R10315 |
PD0332991; Palbociclib Intermediate1 |
Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 wi
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R10316 |
PD0332991; Palbociclib Intermediate2 |
Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 wi
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R10317 |
PD0332991; Palbociclib Intermediate3 |
Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 wi
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R10318 |
Valsartan/sacubitril; LCZ696 Intermediate1 |
LCZ696, consisting of valsartan and sacubitril in 1:1 molar ratio, is an orally
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R10319 |
Valsartan/sacubitril; LCZ696 Intermediate2 |
LCZ696, consisting of valsartan and sacubitril in 1:1 molar ratio, is an orally
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R10320 |
Valsartan/sacubitril; LCZ696 Intermediate3 |
LCZ696, consisting of valsartan and sacubitril in 1:1 molar ratio, is an orally
|
R10321 |
MS37452 |
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R10322 |
Ryuvidine |
Ryuvidine 是一种含有的 SET 结构域的蛋白质 8 (SETD8) 的有效抑制剂,其 IC50 为 0.5 µM,并在体外抑制 H4K20 的甲基化。
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R10323 |
ML190; Indomethacin morpholinylamide |
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R10329 |
Elafibranor;GFT505;GFT-505;GFT 505 |
Elafibranor is an agonist of the peroxisome proliferator-activated receptor-α an
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R10330 |
GFT505; elafibranor E |
Elafibranor是 PPARα/δ 的激动剂,EC50 分别为 45 和 175 nM。
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R10331 |
Cabozantinib S-malate (XL184 S-malate; BMS-907351 S-malate) |
Cabozantinib S-malate (XL184 S-malate) 是一种有效的多受体酪氨酸激酶抑制剂, 抑制VEGFR2,c-Met,Kit,Axl
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R10332 |
Molibresib (Synonyms: GSK 525762A; I-BET 762) |
Molibresib (GSK 525762A; I-BET 762) 是 BET 溴结构域 抑制剂,IC50 为32.5-42.5 nM。
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R10333 |
Navitoclax (Synonyms: ABT-263) |
Navitoclax (ABT-263) 是有效,可口服的 Bcl-2 抑制剂,可与Bcl-xL,Bcl-2, Bcl-w等多种Bcl-2家族蛋白结合,Ki 值
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R10334 |
SU6656 |
SU 6656 is a selective Src family kinase inhibitor with IC50 of 280 nM, 20 nM, 1
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R10336 |
Felbamate; Felbatol |
Felbamate (Felbatol) is an anticonvulsant drug used in the treatment of epilepsy
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R10339 |
PLX-3397; Pexidartinib |
Pexidartinib (PLX3397) is an oral, potent mutil-targeted receptor tyrosine kinas
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R10341 |
BS-181 hydrochloride |
BS-181盐酸盐是CDK7高效选择性抑制剂,IC50值21nM,对CDK1/92/4/5/6/9作用弱。
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R10342 |
GW 627368 |
GW627368 (GW627368X) 是前列腺素受体 EP4 高效选择竞争性抑制剂,还对血栓素受体 TP 有亲和力。
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R10343 |
Bikinin; Abrasin |
Bikinin 是一种非甾体类的,植物性 GSK-3/Shaggy-like kinases 的 ATP 竞争性抑制剂,可激活 BR 信号通路。
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R10344 |
GW9662 |
GW9662 is a selective PPAR antagonist for PPARγ with IC50 of 3.3 nM in a cell-fr
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